Blog dedicated to the continuous education in Gynecology and Endocrinology

 

Serum platelet-activating factor acetylhydrolase activity: Relationship with metabolic syndrome in women with history of gestational diabetes mellitus

DGYE-2010-0018.R1[487612 ]

Derbent, Aysel, carlioglu, ayse; Koca, Cemile; Gumus, Ilknur; Simavlı, Serap; Sevgili, Sema; Karakurt, Feridun; Turhan, Nilgün

Objective. The aim of this study was to evaluate plasma platelet-activating factor acetylhydrolase (PAF-AH) activity in euglycemic women with history of gestational diabetes (GDM), and to explore whether this activity is associated with metabolic syndrome (MS) in this group of women. Methods. more

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Longitudinal changes of adiponectin, carbohydrate, and lipid metabolism in pregnant women at high risk for gestational diabetes

Paradisi DGYE-2009-0133.r1[ID 463717] 7 PAG

To evaluate, in pregnant women at high risk for gestational diabetes (GDM), the longitudinal changes of adiponectin, carbohydrate and lipid metabolism, and to assess their independent value as risk factors for the development of GDM. Fifty women at beginning of pregnancy were studied. more

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The Change in SHBG and the Influence by Gestational Diabetes Mellitus (GDM) in Fetal Period

Zhen Jin, Xiwen Guan, Hong Gao, Lili Shang, Mingyan Gao, Dan Su, Weiwei Li

Objective To investigate the influence of gestational diabetes mellitus (GDM) on the change of SHBG in fetus.

Method 48 pregnant women with GDM and 86 women with normal pregnancy were included in the study. The followings were measured in the serums of pregnant women, amniotic fluids, and umbilical cord serums: glucose, insulin, peptide-C, SHBG, and sex hormones. more

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The protective effect of the ER22/23EK polymorphism against an excessive weight gain during pregnancy


Bertalan, Rita Patócs, Attila; Boyle, Belema; Rigó Jr, János; Rácz, Károly

Abstract: It has been shown that women who gained an excessive weight during pregnancy had an increase in long-term BMI compared to those without an excessive weight gain. Several studies have demonstrated that some polymorphisms of the glucocorticoid receptor gene may influence body composition and metabolic more

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TYPE 2 DIABETES MELLITUS AFTER GESTATIONAL DIABETES: A SYSTEMATIC REVIEW AND META-ANALYSIS.

1) Lancet. 2009 May 23;373(9677):1773-9.

Bellamy L, Casas JP, Hingorani AD, Williams D.

BACKGROUND: Women with gestational diabetes are at increased risk of developing type 2 diabetes, but the risk and time of onset have not been fully quantified. We therefore did a comprehensive systematic review and meta-analysis to assess the strength of association between these conditions and the effect of factors that might modify the risk. more

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