Blog dedicated to the continuous education in Gynecology and Endocrinology

 

PREDICTIVE VALUE FOR PRETERM BIRTH OF ABNORMAL VAGINAL FLORA, BACTERIAL VAGINOSIS AND AEROBIC VAGINITIS DURING THE FIRST TRIMESTER OF PREGNANCY

4) BJOG. 2009 Sep;116(10):1315-24

Donders GG, Van Calsteren K, Bellen G, Reybrouck R, Van den Bosch T, Riphagen I, Van Lierde S.

INTRODUCTION: Abnormal vaginal flora (AVF) before 14 gestational weeks is a risk factor for preterm birth (PTB). The presence of aerobic microorganisms and an inflammatory response in the vagina may also be important risk factors.

AIM: The primary aim of the study was to investigate the differential influences of AVF, full and partial bacterial vaginosis, and aerobic vaginitis in the first trimester on PTB rate. The secondary aim was to elucidate why treatment with metronidazole has not been found to be beneficial in previous studies. more

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CONGENITAL CYTOMEGALOVIRUS INFECTION FOLLOWING PRIMARY MATERNAL INFECTION IN THE THIRD TRIMESTER.

Gindes L, Teperberg-Oikawa M, Sherman D, Pardo J, Rahav G.

BJOG. 2008 Jun;115(7):830-5.

OBJECTIVE: To determine the effect of primary cytomegalovirus (CMV) infection in the third trimester on fetal outcome. DESIGN: Observational study. SETTING: Four perinatal departments in tertiary hospitals in Israel. POPULATION: Twenty-eight women with primary CMV infection acquired after 25 weeks of gestation. more

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RAPID GROUP B STREPTOCOCCI SCREENING USING A REAL-TIME POLYMERASE CHAIN REACTION ASSAY.

Edwards RK, Novak-Weekley SM, Koty PP, Davis T, Leeds LJ, Jordan JA.

Obstet Gynecol. 2008 Jun;111(6):1335-1341.

OBJECTIVE: To estimate the clinical performance characteristics of a real-time polymerase chain reaction (PCR) assay using vaginal/rectal swabs from antepartum (35-37 weeks of gestation) and intrapartum women. METHODS: The assay evaluated is a qualitative, automated, real-time PCR test for the detection of group B streptococci, with results available in approximately 75 minutes. more

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ULTRASOUND PREDICTION OF SYMPTOMATIC CONGENITAL CYTOMEGALOVIRUS INFECTION.

Am J Obstet Gynecol. 2008 Apr;198(4):380.e1-7.
Guerra B, Simonazzi G, Puccetti C, Lanari M, Farina A, Lazzarotto T, Rizzo N.

OBJECTIVE: The objective of the study was to assess the effectiveness of ultrasound in the antenatal prediction of symptomatic congenital cytomegalovirus (CMV) infection. STUDY DESIGN: The sonograms of 650 fetuses from mothers with primary CMV infection were correlated to fetal or neonatal outcome. Infection status was disclosed by viral urine isolation at birth or CMV tissue inclusions at autopsy. more

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FIRST TRIMESTER BACTERIAL VAGINOSIS, INDIVIDUAL MICROORGANISM LEVELS, AND RISK OF SECOND TRIMESTER PREGNANCY LOSS AMONG URBAN WOMEN.

Fertil Steril. 2007 Nov;88(5):1396-403.
Nelson DB, Bellamy S, Nachamkin I, Ness RB, Macones GA, Allen-Taylor L.

OBJECTIVE: To examine the role of first trimester bacterial vaginosis (BV) and level of BV-associated microorganisms, diagnosed using the Nugent gram stain criteria and the risk of second trimester pregnancy loss among urban women.
DESIGN: Prospective cohort study.
SETTING: Urban prenatal care clinics. more

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