Blog dedicated to the continuous education in Gynecology and Endocrinology

 

Divergent Effects of Ethinylestradiol-Drospirenone and Flutamide-Metformin on Follistatin in Adolescents and Women with Hyperinsulinemic Androgen Excess

DGYE-2010-0065.R1[490612]

Ibanez, L; Diaz, Marta; Lopez-Bermejo, Abel; de Zegher, Francis

Randomized studies have disclosed that ethinylestradiol-drospirenone and flutamide-metformin have divergent effects on the body adiposity and adipokines of adolescents and young women with hyperinsulinemic androgen excess. We have now tested in 41 patients from those original studies whether the divergent effects on body adiposity could be mediated by divergent levels of follistatin, an adipokine that promotes subcutaneous adipogenesis. more

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CLINICAL AND THERAPEUTICAL ASPECTS OF PCOS

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Insulin regulates both basal and stimulated gonadotropins secretion in PCOS patients: different effect of metformin, hypocaloric and low glucidic diet
Glinski L

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Association between serum adipocyte factor and insulin resistance in PCOS
Huang W

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Policystic ovary syndrome and benign breast disease: two aspects of the same dysmetabolic condition
Londero AP

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Follicular function and metabolic assessment in obese women with polycystic ovary syndrome: Antimullerian hormone after insulin-sensitizing therapy
Ricciardi L

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Metformin inhibits aromatase via an ERK-mediated pathway
Rice S

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Autoimmunity and Polycystic Ovary Syndrome
Rinaldi E

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Metabolic features and uterine artery color doppler analysis in polycistic ovary syndrome (PCOS) and control women
Signori C

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Genetic predisposition of polycystic ovarian disease: Report of clusters within 10 large families; inclusion of novel signs and describing male PCOD
Talaee RZ

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Atherogenic metabolic profile in PCOS patients: role of obesity and hyperandrogenism

Castelo-Branco, Camil (contact); Steinvarcel, Florencia; Osorio, Alois; Ros, Cristina; Balasch, J – DGYE-2010-0087 [481025]

Objective: To investigate metabolism and androgenic profile in a cohort of women with Polycystic Ovary Syndrome (PCOS) divided according to Rotterdam phenotypes and body mass index (BMI). Design: case-control study. Patients: 223 PCOS women and 25 healthy control women were studied. Methods: Patients and controls were subdivided into three groups according to their BMI and according to Rotterdam criteria of PCOS. more

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Clinical cases: hyperandrogenic woman with hyrsutism, acne and no will of pregnancy

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Clinical cases: hyperandrogenic woman with hyrsutism, acne and no will of pregnancy
Kiesel Ludwig

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Comprehensive clinical management of hirsutism

Castelo-Branco, Camil DGYE-2009-0232.r1 10 PAG

Hirsutism is an excessive body and facial hair growth in women in locations where is normally minimal or absent following a hair-male pattern. For this reason is not uncommon that hirsutism raises psychological, cosmetic and social concerns. more

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