DGYE-2010-0065.R1[490612]

Ibanez, L; Diaz, Marta; Lopez-Bermejo, Abel; de Zegher, Francis

Randomized studies have disclosed that ethinylestradiol-drospirenone and flutamide-metformin have divergent effects on the body adiposity and adipokines of adolescents and young women with hyperinsulinemic androgen excess. We have now tested in 41 patients from those original studies whether the divergent effects on body adiposity could be mediated by divergent levels of follistatin, an adipokine that promotes subcutaneous adipogenesis. more

Castelo-Branco, Camil (contact); Steinvarcel, Florencia; Osorio, Alois; Ros, Cristina; Balasch, J – DGYE-2010-0087 [481025]

Objective: To investigate metabolism and androgenic profile in a cohort of women with Polycystic Ovary Syndrome (PCOS) divided according to Rotterdam phenotypes and body mass index (BMI). Design: case-control study. Patients: 223 PCOS women and 25 healthy control women were studied. Methods: Patients and controls were subdivided into three groups according to their BMI and according to Rotterdam criteria of PCOS. more

Castelo-Branco, Camil DGYE-2009-0232.r1 10 PAG

Hirsutism is an excessive body and facial hair growth in women in locations where is normally minimal or absent following a hair-male pattern. For this reason is not uncommon that hirsutism raises psychological, cosmetic and social concerns. more