Blog dedicated to the continuous education in Gynecology and Endocrinology

 

Sertoli- Leydig cell tumor in a 13- year old girl

DGYE-2009-0301.R1[495427] ,
Böttcher, Bettina Hinney, Bernd; Keyser, Johanna; Kühnle, Ingrid; Schweyer, Stefan; Emons, Günter

Sertoli- Leydig cell tumors account for less than 0.2% of ovarian malignancies. We describe the case of a Sertoli- Leydig cell tumor in a 13-year old girl who presented with symptoms of hyperandrogenism. We give an overview over current literature and discuss options of therapy of rare Sertoli- Leydig cell tumors.

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HSP10 regulated apoptosis in the cultured mouse ovarian granulosa cells

DGYE-2009-0257.R1[487594]

Liu, Jiayin (contact); Ling, Jing; Zhao, Kaokao; Cui, Yugui; Wang, Xinru; Li, Ying; Li, Mei; Xue, Kai; Ma, Xiang

Objectives: To study the roles of HSP10 in the regulation of mouse ovarian granulosa cell (GC) apoptosis, and define the possible role of HSP10 in the development of PCOS. Methods: Mouse HSP10 siRNA and recombinant adenoviruses over-expressing HSP10 were constructed and transfected into cultured GCs. After 48 h, the expression of HSP10 was confirmed by Western blot. more

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Characterisation of early ovarian cancer biomarkers

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Characterisation of early ovarian cancer biomarkers Meehan K

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Metabolomics in serum of ovariectomized rats and those exposed to 17β-estradiol and genistein

Ni, Xin (contact); Zhu, Xiaoyan; Liu, Xinru; He, Ping; Cao, Buqing; lv, Yonghai; Zhang, Weidong – DGYE-2010-0037[487615 ]

Objective Metabolites profiling provides global insights in characterizations and interactions of metabolites under specific physiological or pathologic states.
The aim of this study was to examine serum metabolic changes in bilateral ovariectomized (OVX) rats and those exposed to 17β-estradiol (E2, 30 μg/kg•bw, sc.) or genistein (50 μg/kg•bw, sc.) for 12 weeks. more

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Molecular mechanisms regulating rapid vascular dilation by estrogen receptors

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Molecular mechanisms regulating rapid vascular dilation by estrogen receptors
Karas Richard

(14th World Congress of Gynecological Endocrinology – March 4-7 2010)

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