Blog dedicated to the continuous education in Gynecology and Endocrinology

 

MECHANISMS OF TRANSCOELOMIC METASTASIS IN OVARIAN CANCER

6) Lancet Oncology 2006; 7:925-934
Tan DSP, Agarwal R, Kaye SB

Metastasis from epithelial ovarian cancer can occur via the transcoelomic, haematogeneous, or lymphatic route. Of these, transcoelomic metastasis is the most common, and is responsible for the greatest morbidity and mortality in women with this disease. Unfortunately, very little is known about the mechanisms behind this process. more

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HORMONAL THERAPY FOR MENOPAUSE AND BREAST-CANCER RISK BY HISTOLOGICAL TYPE: A COHORT STUDY AND META-ANALYSIS

5) Lancet Oncology 2006; 7:910-918
Reeves GK,   Beral V,   Green J,   Gathani T, Bull D, for the Million Women Study Collaborators

Background: Little information is available on how the risk of breast cancer associated with the use of hormone therapy for menopause varies by histological type. We aimed to describe such associations for eight histological types of breast cancer. more

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MODIFIERS OF RISK OF HEREDITARY BREAST CANCER

4) Oncogene. 2006 Sep 25;25(43):5832-6
Narod SA.

Mutations in the BRCA1 and BRCA2 genes confer a high lifetime risk of breast and ovarian cancer. The risk varies from individual to individual, and it appears that the risk has increased in recent generations. These observations imply that non-genetic factors may modify the inherited risk. more

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CLINICAL MANAGEMENT OF BRCA1 AND BRCA2 MUTATION CARRIERS

3) Oncogene. 2006 Sep 25;25(43):5825-31
Domchek SM, Weber BL.

The cancer susceptibility genes BRCA1 and BRCA2 appear to be responsible for virtually all hereditary breast ovarian families, and a smaller subset of hereditary site-specific breast cancer families. more

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HYPERTENSION, DIURETICS AND BREAST CANCER RISK

2) J Hum Hypertens. 2006 Oct;20(10):727-32
Largent JA, McEligot AJ, Ziogas A, Reid C, Hess J, Leighton N, Peel D, Anton-Culver H.

It is unclear whether hypertension and antihypertensive medication use are associated with breast cancer. In order to examine these associations, we conducted a case-control study among women aged 50-75 years. Breast cancer cases were ascertained via a population-based cancer registry (n=523) and controls were ascertained via random-digit-dialing (n=131). more

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